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ResFouriONet: A Residual Fourier Operator Network with Synthetic Data Generation for Real-Time Laser-Induced Bioheat

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ResFouriONet accurately models laser-induced heating in tissues using a novel deep operator network. This approach enables real-time predictions for biomedical applications, reducing computational costs and reliance on extensive data.

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Area of Science:

  • Biomedical Engineering
  • Computational Physics
  • Medical Imaging

Background:

  • Accurate modeling of laser-tissue interactions is crucial for medical applications like brain imaging and laser therapies.
  • Traditional methods (e.g., Monte Carlo simulations) are computationally intensive, hindering real-time applications.
  • Operator learning offers scalability but faces challenges with extrapolation and data generation.

Purpose of the Study:

  • To develop a computationally efficient deep operator network for modeling 2D transient bioheat transfer with parametric laser sources.
  • To introduce a novel synthetic data generation scheme to reduce dependence on costly Monte Carlo simulations.
  • To enable accurate, real-time prediction of laser-induced thermal effects.

Main Methods:

  • Introduced ResFouriONet, a residual deep operator network with a dual-pathway architecture (Fourier and cascaded residual sub-branches) and self-attention.
  • Developed a synthetic laser source function generation scheme using Gaussian profiles, exponential decay, and random perturbations.
  • Evaluated performance on unseen synthetic data and Monte Carlo-generated source functions.

Main Results:

  • ResFouriONet achieved a 5x reduction in prediction error compared to vanilla deep operator networks.
  • Attained an average relative error of 0.93% on synthetic data and 1.45% on Monte Carlo-generated data.
  • Demonstrated accurate, real-time prediction capabilities with fewer parameters.

Conclusions:

  • The proposed ResFouriONet architecture and data generation strategy enable efficient and accurate modeling of laser-induced heating.
  • This facilitates simulation-free planning and control in biomedical imaging and laser therapies.
  • Paves the way for real-time thermal management in laser-based medical procedures.