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Successful Treatment with Sulbactam-Durlobactam for Severe Acute Pancreatitis Complicated by Extensively

Zhengmao Ge1, Li Li1, Longxin Wang1

  • 1Department of Critical Care Medicine, The 967 Hospital, Joint Logistics Support Force of PLA, Dalian, 116021, People's Republic of China.

Infection and Drug Resistance
|March 20, 2026
PubMed
Abstract

Insights

This case study highlights the successful use of sulbactam-durlobactam for severe acute pancreatitis (SAP) with extensively drug-resistant Acinetobacter baumannii (XDR-AB) infections. The new treatment achieved clinical and microbiological cure in a patient refractory to other therapies.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Pharmacology

Background:

  • Severe acute pancreatitis (SAP) with multi-site infections caused by extensively drug-resistant Acinetobacter baumannii (XDR-AB) presents significant treatment challenges.
  • Conventional antimicrobial regimens often fail in these complex cases, necessitating novel therapeutic approaches.
Keywords:
Acinetobacter baumanniicase reportdrug resistancesevere acute pancreatitissulbactam-durlobactam

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