Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

996
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
996
Respiratory Volumes01:15

Respiratory Volumes

3.4K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
3.4K
Respiratory Capacities01:24

Respiratory Capacities

1.6K
Respiratory capacities are crucial indicators of lung function, representing the maximum amount of air an individual's respiratory system can handle during various breathing phases.
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...
1.6K
Lung Capacity01:47

Lung Capacity

57.5K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
57.5K
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

1.4K
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
1.4K
Physical Assessment of the Respiratory Tract II: Inspection01:27

Physical Assessment of the Respiratory Tract II: Inspection

1.2K
Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The combined use of inhaled nitric oxide and molecular hydrogen in patients with post-COVID-19 syndrome].

Terapevticheskii arkhiv·2026
Same author

[Pulmonary health: From neonatology to gerontology].

Terapevticheskii arkhiv·2025
Same author

[Ferritin as a biomarker of aging: geroprotective peptides of standardized human placental hydrolysate. A review].

Terapevticheskii arkhiv·2024
Same author

[Prevention and treatment of COVID-19 based on post-genomic pharmacological analysis: Systematic computer analysis of 290,000 scientific articles on COVID-19].

Terapevticheskii arkhiv·2024
Same author

[Pulmonary fibrosis in patients with COVID-19: A review].

Terapevticheskii arkhiv·2023
Same author

[Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19].

Terapevticheskii arkhiv·2022

Related Experiment Video

Updated: Mar 21, 2026

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

14.8K

[Non-respiratory lung function (problem status)].

A G Chuchalin1

  • 1Pirogov Russian National Research Medical University (Pirogov University).

Terapevticheskii Arkhiv
|March 20, 2026
PubMed
Summary
This summary is machine-generated.

Non-respiratory lung function (NFL) research reveals the lungs

Keywords:
biological markersexhaled breath condensateimmunological function of the lungsmetabolic function of the lungs

More Related Videos

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
06:11

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

6.5K
Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.4K

Related Experiment Videos

Last Updated: Mar 21, 2026

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

Published on: March 15, 2018

14.8K
Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
06:11

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

6.5K
Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
08:44

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies

Published on: February 2, 2024

1.4K

Area of Science:

  • Pulmonary Medicine
  • Biochemistry
  • Immunology

Background:

  • The European Respiratory Society has standardized the study of volatile compounds in exhaled air.
  • The lungs perform metabolic, immunological, and endocrine functions beyond respiration.
  • Non-respiratory lung function (NFL) research has gained significant traction over the past two decades.

Purpose of the Study:

  • To explore the multifaceted non-respiratory functions of the lungs.
  • To highlight the role of pulmonary parenchyma, alveolocytes, macrophages, and endothelial cells in various physiological processes.
  • To investigate the potential of lung function markers in disease diagnosis.

Main Methods:

  • Standardized analysis of volatile organic and inorganic compounds in exhaled air and condensate.
  • Examination of pulmonary parenchyma's metabolic functions, including water-electrolyte balance and biologically active amine/peptide regulation.
  • Assessment of alveolocyte and alveolar macrophage roles in surfactant metabolism.
  • Investigation of pulmonary capillary endotheliocytes and the renin-angiotensin system.
  • Analysis of the respiratory system's immunological functions, including mucosal immunity and neuroepithelial roles.

Main Results:

  • The lungs actively regulate water-electrolyte metabolism and synthesize/recycle surfactant.
  • Pulmonary capillary endothelium plays a role in the renin-angiotensin system.
  • The respiratory system functions as an active immunological organ, contributing to innate and acquired immunity.
  • Neuroepithelium in the respiratory tract influences cell differentiation and lung tissue morphogenesis.
  • Potential biological markers for diseases like asthma, COPD, lung cancer, and pneumonia have been identified.

Conclusions:

  • Non-respiratory lung functions are crucial and diverse, encompassing metabolic, immunological, and endocrine roles.
  • Exhaled air condensate analysis, particularly proteomic studies, offers a promising avenue for discovering novel biomarkers.
  • Further research into the lungs' endocrinological functions is warranted.