Primary Malignant Pulmonary Glomus Tumor: A Case Report and Literature Review

Malignant glomus tumors originating from the lungs are relatively rare. We report a case of primary malignant pulmonary glomus tumor in a 41-year-old female. Chest CT revealed an 8 × 6 cm mass in the upper lobe of the right lung with multiple spotted calcifications, with uneven enhancement on enhanced scans; multiple metastatic nodules can be seen in both lungs; enlarged lymph nodes can be seen in the mediastinum and right hilar lobe. The pathological diagnosis of right lung puncture was malignant pulmonary glomus tumor. Chemotherapy and targeted therapy with arotinib hydrochloride were used, and survival was still observed after 36 months of follow-up. The clinical manifestations of primary malignant pulmonary glomus tumor lack specificity. The imaging manifestations are well-defined nodules or masses, with peripheral enhancement on enhanced scans. The imaging manifestations of benign and malignant pulmonary glomus tumor overlap with other lung tumors, making differential diagnosis difficult. The diagnosis is mainly based on pathology and immunohistochemical.