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Updated: Mar 24, 2026
Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
Published on: September 8, 2023
Pectoral muscle cross-sectional area correlates with bone mineral density in postmenopausal women
Min Xue1, Xiao-Hui You2, Xiong-Yi Wang3
1Department of Ultrasound, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Objective:
To evaluate the correlation between pectoralis muscle and bone mineral density (BMD) in postmenopausal women with estrogen deficiency. Furthermore, the degree of bone loss can be initially assessed by chest muscle area.
Methods:
This is a retrospective study. 500 subjects were included in this study from August 2023 to August 2024. The participants were classified into normal, osteopenia, and osteoporosis groups. We analyzed the correlation between the age, BMI, PMA and BMD. The correlation between PMA and BMD was tested by multiple linear regression, after correction for age and BMI.
Results:
A total of 338 subjects were finally included in the study after exclusion criteria. There was good agreement between the two measurement workers (ICC = 0.980, p < 0.05). Age, BMI and PMA were strongly correlated with BMD. PMA was positively correlated with lowest BMD (r = 0.448). Multiple linear regression showed no multicollinearity between age, BMI and PMA. The formula was: Lowest BMD = 0.858 - 0.005 * age + 0.006 * BMI + 0.005 * PMA.
Conclusions:
Decreased muscle mass increases the risk of osteoporosis prevalence. Simple measurements from routine chest CT can provide information about BMD and offer a way to evaluate osteoporosis.
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