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Extracapillary Proliferation Superimposed on Primary Membranous Glomerulonephritis: A Case Report
Oumaima El Kaoua1, Nabil Hamouche2, Mariam Chettati3
1Department of Nephrology, Centre Hospitalier Universitaire (CHU) Mohammed VI Marrakech, Marrakesh, MAR.
Cureus
|March 23, 2026
Summary
Primary membranous glomerulonephritis can rarely progress to severe kidney failure. This case highlights the importance of monitoring patients for rapid disease progression and potential crescentic transformation.
Area of Science:
- Nephrology
- Internal Medicine
- Pathology
Background:
- Primary membranous glomerulonephritis (pMGN) is a common cause of nephrotic syndrome in adults.
- Initial presentation often involves preserved renal function, necessitating careful monitoring.
- Progression to end-stage renal disease (ESRD) can occur, though crescentic transformation is uncommon.
Keywords:
chronic hemodialysiscrescentimmunosuppressionmembranous nephropathynephrotic syndromeprimary membranous nephropathyrenal failureMore Related Videos
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