Related Experiment Video
Updated: Mar 25, 2026

10:47
Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice
Published on: April 14, 2011
17.5K
A 9-Year-Old Girl with Persistent Fevers and Lethargy
Aoun Zaib Khan1, Farva Zaib Khan1, Ahmed Sajid1
1from the Pediatric Residency Program at MetroHealth Medical Center of the Case Western Reserve University School of Medicine.
NEJM Evidence
|March 24, 2026
Summary
This case report details a 9-year-old girl with prolonged fevers and malaise. The diagnostic process, involving clinical examination and testing, led to a final diagnosis.
Area of Science:
- Pediatrics
- Internal Medicine
- Clinical Case Reports
Background:
- Morning Report is a traditional medical education conference.
- It facilitates collaborative learning through case presentations.
- This section aims to replicate this interactive learning experience for readers.
Purpose of the Study:
- To present an interesting pediatric case for diagnostic learning.
- To guide readers through the differential diagnosis process.
- To illustrate the refinement of diagnostic possibilities based on clinical progression.
Main Methods:
- A 9-year-old female patient presented with prolonged fevers and malaise.
- Diagnostic approach included patient history, physical examination, and laboratory testing.
- An illness script was developed to guide the diagnostic reasoning.
Main Results:
- The initial presentation suggested a broad differential diagnosis.
- Clinical course and further investigations allowed for refinement of the differential.
- A definitive diagnosis was established after evaluating the patient's progression.
Conclusions:
- This case highlights the importance of a systematic approach to pediatric fevers.
- Interactive case reviews enhance diagnostic skills in medical trainees and clinicians.
- The presented case serves as an educational tool for complex presentations.
Related Concept Videos
Patterns of Fever
4.3K
Before understanding the types and patterns of fever, it is essential to know its phases.
4.3K
Increased Body Temperature
7.6K
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
7.6K
Types of Fever
1.4K
Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Here are the different types of fever:
1.4K
Methods of reducing fever
1.5K
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Pharmacological Methods of Reducing Fever:
1.5K
Atypical Pneumonia
17
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
17
Pulmonary Tuberculosis III
1.3K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
1.3K