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How to implement a radiologist led whole-body MRI screening program
Andrea S Kierans1, Keith D Hentel1, Katerina Dodelzon1
1Weill Cornell Medical College, Department of Radiology, New York City, NY, USA.
Radiology Advances
|March 25, 2026
Summary
Screening whole-body MRI (WB-MRI) shows promise for early disease detection but faces controversy in asymptomatic individuals due to potential harms. Radiologists must guide its evidence-based, patient-centered expansion.
Area of Science:
- Radiology
- Medical Imaging
- Diagnostic Medicine
Background:
- Screening whole-body MRI (WB-MRI) adoption is increasing, driven by consumer demand and private platforms.
- Its utility is established in high-risk groups, but use in asymptomatic individuals is debated due to concerns like false positives and lack of survival data.
Purpose of the Study:
- To review current evidence on screening WB-MRI.
- To outline program development and implementation within an academic radiology practice.
- To discuss downstream implications, cost-effectiveness, and the role of radiologists in guiding WB-MRI expansion.
Main Methods:
- Literature review of current evidence on screening WB-MRI.
- Description of an academic radiology practice's WB-MRI program development and implementation.
- Discussion of ethical considerations, cost-effectiveness, and future directions.
Main Results:
- WB-MRI is gaining traction for early disease detection, particularly from direct-to-consumer marketing.
- Controversies persist regarding its use in asymptomatic individuals, citing low yield and potential overdiagnosis.
- Radiologists' proactive engagement is crucial for evidence-based and patient-centered implementation.
Conclusions:
- The popularity of WB-MRI is rising, necessitating careful consideration by radiologists.
- Radiologists must ensure scientific rigor, ethical oversight, and multidisciplinary collaboration in WB-MRI expansion.
- Defining best practices for screening WB-MRI is essential as its use broadens beyond traditional indications.
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