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Whole-body PET/MRI of Pediatric Patients: The Details That Matter
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How to implement a radiologist led whole-body MRI screening program.

Andrea S Kierans1, Keith D Hentel1, Katerina Dodelzon1

  • 1Weill Cornell Medical College, Department of Radiology, New York City, NY, USA.

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This summary is machine-generated.

Screening whole-body MRI (WB-MRI) shows promise for early disease detection but faces controversy in asymptomatic individuals due to potential harms. Radiologists must guide its evidence-based, patient-centered expansion.

Keywords:
cancer screeningpreventative imagingscreening whole-body MRI

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Area of Science:

  • Radiology
  • Medical Imaging
  • Diagnostic Medicine

Background:

  • Screening whole-body MRI (WB-MRI) adoption is increasing, driven by consumer demand and private platforms.
  • Its utility is established in high-risk groups, but use in asymptomatic individuals is debated due to concerns like false positives and lack of survival data.

Purpose of the Study:

  • To review current evidence on screening WB-MRI.
  • To outline program development and implementation within an academic radiology practice.
  • To discuss downstream implications, cost-effectiveness, and the role of radiologists in guiding WB-MRI expansion.

Main Methods:

  • Literature review of current evidence on screening WB-MRI.
  • Description of an academic radiology practice's WB-MRI program development and implementation.
  • Discussion of ethical considerations, cost-effectiveness, and future directions.

Main Results:

  • WB-MRI is gaining traction for early disease detection, particularly from direct-to-consumer marketing.
  • Controversies persist regarding its use in asymptomatic individuals, citing low yield and potential overdiagnosis.
  • Radiologists' proactive engagement is crucial for evidence-based and patient-centered implementation.

Conclusions:

  • The popularity of WB-MRI is rising, necessitating careful consideration by radiologists.
  • Radiologists must ensure scientific rigor, ethical oversight, and multidisciplinary collaboration in WB-MRI expansion.
  • Defining best practices for screening WB-MRI is essential as its use broadens beyond traditional indications.