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Updated: Mar 27, 2026

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
[Preterm birth: definitions, epidemiology, preventive measures]
1Département de médecine néonatale, hôpital Cochin-Port Royal, AP-HP, Paris, France, Université Paris Cité, Centre de recherche en épidémiologie et statistiques (CRESS), Inserm, INRAE, Paris, France.
Insights
Preterm birth, before 37 weeks gestation, impacts millions globally. Survival rates for premature infants significantly increase with each week of gestation, highlighting the importance of gestational age.
Area of Science:
- Obstetrics and Gynecology
- Neonatology
- Public Health
Abstract:
Preterm birth is defined as any birth occurring before 37 completed weeks of gestation (WG). It affects 9.9% of live births, representing 13.4 million births a year worldwide. In France, preterm birth rate is of 7.0%. The causes of preterm birth can be grouped into 3 main categories: infectious/inflammatory, vascular, and other. Risk factors, preventive measures, and impact on the child's health depend of these causes. Risks of death and of neonatal complications are strongly associated with gestational age at birth. Other factors are also involved, such as birth weight (fetal growth restriction) or the administration of antenatal corticosteroids. In 2020 in France, survival rates were of 47% for children born alive at 24 WG, 80% at 26 WG, 92% at 28 WG and 97% at 31 WG.
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