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Percutaneous Aspiration for IVDU-Associated Infective Endocarditis: A Comparative Case Series

Ghulam Mujtaba Ghumman1, Anas Noman1, Tarif Kanaan1

  • 1Cardiovascular Diseases, Mercy Health Saint Vincent Medical Center, Toledo, Ohio, USA.

JACC. Case Reports
|March 25, 2026
PubMed
Abstract

Insights

Transcatheter aspiration using AngioVac or Penumbra offers a new treatment for intravenous drug use-associated tricuspid valve infective endocarditis in patients unsuitable for surgery, successfully clearing bacteremia and stabilizing patients.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Infectious Diseases

Background:

  • Management of infective endocarditis (IE) in intravenous drug users (IVDU) poses challenges, particularly when tricuspid valve (TV) involvement occurs and surgery is not an option.
  • High-risk patients with IVDU-associated TV IE often present with persistent bacteremia and septic pulmonary emboli, complicating treatment decisions.
Keywords:
drug abuseechocardiographyendocarditistranscathetertricuspid valve

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