iCare quantitative CT shows a higher detection rate of hip osteoporosis compared with Mindways quantitative CT

Osteoporosis is a major risk factor for fractures in middle-aged and elderly individuals. Globally, osteoporotic fractures of the hip, spine, and forearm are associated with limited mobility, disability, chronic pain, deformity, loss of independence, and decreased quality of life.

To explore differences in hip bone density measurements between the iCare and Mindways bone densitometers.

The iCare and Mindways quantitative computed tomography (QCT) post-processing software were used to measure high-, medium-, and low-density vertebrae within a European Spine Phantom (ESP) to compare the average values obtained with each QCT software and to assess potential differences. Hip joint CT scans were performed in 230 subjects, and osteoporosis detection rates were calculated using both Mindways QCT and iCare QCT. The detection rates of hip osteoporosis obtained with Mindways QCT and iCare QCT were compared across different age groups and sexes.

There were no statistically significant differences (p > 0.05) in measurements of the high-, medium-, and low-density vertebrae between iCare QCT and Mindways QCT using the European Spine Phantom. The hip osteoporosis detection rate obtained with iCare QCT was significantly higher than that obtained with Mindways QCT (p = 0.01). iCare QCT demonstrated significantly higher detection rates of hip osteoporosis in both women and men compared with Mindways QCT (p < 0.05). Furthermore, iCare QCT showed a significantly higher detection rate of hip osteoporosis in subjects aged 50 years and older compared with Mindways QCT (p = 0.02).

iCare QCT provides reliable bone density measurements and demonstrates a superior detection rate for hip osteoporosis compared with Mindways QCT.