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Related Concept Videos

Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Mar 27, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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Home-Based Visual Field Monitoring for Open-Angle Glaucoma Using a Web-Enabled Quantitative Perimeter (Perimouse): An

Xiaoyuan Shen1, Zidong Chen1, Wenxin Yang1

  • 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, People's Republic of China.

Clinical Ophthalmology (Auckland, N.Z.)
|March 26, 2026
PubMed
Summary

Home-based visual field monitoring using Perimouse is reliable and acceptable for glaucoma patients. This self-management tool shows consistency with standard tests and patient preference for usability.

Keywords:
glaucomaremote patient monitoringtelemedicinevisual field tests

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Area of Science:

  • Ophthalmology
  • Medical Technology
  • Patient Monitoring

Background:

  • Glaucoma management requires regular visual field monitoring.
  • Current methods may present challenges for home-based patient self-management.
  • Developing reliable remote monitoring tools is crucial for patient care.

Purpose of the Study:

  • To evaluate the reliability and acceptability of a novel online perimeter, Perimouse, for home-based visual field monitoring in glaucoma patients.
  • To compare the performance of Perimouse with the Humphrey Field Analyzer (HFA).
  • To assess patient satisfaction with remote visual field testing.

Main Methods:

  • A prospective study involving 60 glaucoma patients (97 eyes) using Perimouse for monthly remote visual field tests over six months.
  • Unsupervised home testing with video and written instructions.
  • Comparison with Humphrey Field Analyzer (HFA) tests conducted pre- and post-trial.
  • Patient compliance and acceptability assessed via follow-up rates and questionnaires.

Main Results:

  • A 67.01% follow-up completion rate was maintained at six months.
  • Perimouse demonstrated overall consistency with HFA, though variability increased with decreased sensitivity.
  • Bland-Altman analysis showed minimal mean differences in Perimouse Mean Deviation (MD) over time.
  • Perimouse showed higher patient preference for stress relief, visual comfort, and cost-effectiveness compared to HFA (P<0.05).

Conclusions:

  • Glaucoma patients can successfully perform remote visual field monitoring using Perimouse in an unsupervised setting.
  • Perimouse shows potential as a tool to support home-based visual field monitoring.
  • The technology may enhance self-management capabilities for individuals with glaucoma.