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Complications and Outcomes in Patients With Inflammatory Arthritis Undergoing Minimally Invasive Lumbar Fusion
Cole Kwas1, Kevin J Disilvestro1, Nishtha Singh1
1Hospital for Special Surgery.
Clinical Spine Surgery
|March 26, 2026
Summary
Minimally invasive lumbar fusion shows comparable outcomes for patients with and without inflammatory arthritis. This study found no significant differences in complications or clinical results, supporting its use in both patient groups.
Area of Science:
- Spine surgery
- Orthopedics
- Rheumatology
Background:
- Patients with inflammatory arthritis (IA) have increased spinal pathology risk.
- Limited data exists on minimally invasive lumbar fusion outcomes in IA patients.
Purpose of the Study:
- Compare 90-day complication rates and clinical outcomes.
- Evaluate minimally invasive lumbar fusion in IA versus non-IA patients.
Main Methods:
- Retrospective cohort study (2017-2023).
- Included 669 patients (23 IA, 646 non-IA) with degenerative lumbar spine pathology.
- Compared demographics, perioperative variables, complications, and patient-reported outcomes (PROMs).
Main Results:
- No significant differences in 90-day complications, reoperations, or readmissions between IA and non-IA cohorts.
- IA cohort showed PROM improvements; PROM scores and MCID achievement were comparable.
- Case-control matching confirmed no significant differences in outcomes.
Conclusions:
- Minimally invasive lumbar fusion yields similar clinical outcomes for IA and non-IA patients.
- The procedure is a viable option for IA patients with degenerative lumbar spine disease.
