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Intraocular Pressure Measurement Variability Associated With Face Mask Use
Ortal Fogel Tempelhof1, Yael Reich2, Rony Rachmiel1
1Department of Ophthalmology, Tel Aviv Sourasky Medical Center (Affiliated to The Faculty of Medicine, Tel Aviv University, Israel), Tel Aviv.
Journal of Glaucoma
|March 26, 2026
Summary
Face masks can impact intraocular pressure (IOP) measurements, with significant clinical changes observed in about one-third of glaucoma patients. Further IOP evaluation without masks is recommended for accurate clinical decisions.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Public Health Measures
Background:
- Intraocular pressure (IOP) is a critical, manageable factor in glaucoma, a leading cause of blindness.
- Face masks are essential for reducing respiratory infection transmission, as seen during global outbreaks like COVID-19.
Purpose of the Study:
- To evaluate the effect of wearing face masks on intraocular pressure (IOP) measurements.
- To understand potential clinical implications for glaucoma management.
Main Methods:
- A prospective, randomized, controlled, and blinded clinical study.
- Adult patients underwent IOP measurements using Goldmann applanation tonometry with surgical masks, KN95 masks, and without a mask (control).
Main Results:
- No statistically significant differences in IOP readings were found between mask conditions (P=0.116).
- However, 34.0% of patients showed an IOP difference of 3 mm Hg or more.
- These variations were not statistically significant (P=0.546) and unaffected by gender, laterality, medication, or prior treatments.
Conclusions:
- Face masks have a multi-factorial and inconsistent impact on IOP measurements.
- Clinical significance in IOP variations was noted in approximately one-third of patients.
- Factors like mask fit and breathing patterns may influence IOP readings, warranting further clinical consideration.

