Addressing Chronic Steatotic Liver Disease through Community Partnerships, Integrated Behavioral Interventions, and
Hayley Treloar Padovano1, Mollie A Monnig1, Ardhys De Leon1
1Center for Alcohol and Addiction Studies, Center for Addiction and Disease Risk Exacerbation, Brown University, Providence, RI.
A new community-based model successfully screened for Metabolic and Alcohol-associated Liver Disease (MetALD) using point-of-care diagnostics. This approach identified silent liver conditions in an underserved population, enabling early intervention.
Area of Science:
- Hepatology
- Public Health
- Preventive Medicine
Background:
- Metabolic and Alcohol-associated Liver Disease (MetALD) poses a significant health burden, particularly in underserved communities.
- Early detection and intervention are crucial for managing MetALD and preventing advanced liver disease.
- Traditional healthcare access barriers often delay diagnosis in vulnerable populations.
Purpose of the Study:
- To assess the feasibility of a community-based, point-of-care (POC) screening and intervention model for MetALD.
- To target an underserved population in Rhode Island for MetALD screening.
- To integrate diagnostics and lifestyle interventions within a community clinic setting.
Main Methods:
- A partnership between Brown University CADRE and Clínica Esperanza/Hope Clinic (CEHC) was established.
- Electronic health record (EHR) screening was followed by on-site FibroScan® imaging.
- Motivational Interviewing (MI) lifestyle interventions were provided to participants.
Main Results:
- Preliminary pilot data revealed significant prevalence of liver conditions.
- Liver stiffness (fibrosis) was identified in 21% of participants.
- Steatosis was detected in 57% of participants, with all cases previously undiagnosed.
Conclusions:
- Integrating POC diagnostics with culturally sensitive interventions in community clinics is feasible.
- This model effectively bypasses traditional healthcare access barriers.
- Early detection of "silent" liver disease at treatable stages is achievable in underserved populations.
More Related Videos
04:14Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution
Published on: April 16, 2019
12:24A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Related Concept Videos
Chronic Pancreatitis II: Collaborative Care
Assessment:
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
