Comparing a Red and Blue Light-Emitting Diode Light Device With an Existing Blue Light Device for At-Home Treatment...

Area of Science:

• Dermatology
• Phototherapy
• Medical Devices

Background:

• Red and blue light offer complementary benefits for acne treatment.
• Acne vulgaris is a common skin condition affecting millions worldwide.

Purpose of the Study:

• To compare the efficacy and safety of a combination red and blue light device (RBL) versus a blue light device (BL) for at-home acne treatment.
• To evaluate the impact of RBL and BL on mild-to-moderate inflammatory acne.

Main Methods:

• An open-label, randomized-controlled trial involving 30 participants.
• Participants used either the RBL or BL device daily for 8 weeks.
• Follow-up assessments were conducted at 4 and 8 weeks.

Main Results:

• The RBL device significantly reduced total acne lesions at 4 and 8 weeks.
• Both RBL and BL significantly reduced inflammatory lesions.
• The RBL group showed a significantly greater reduction in investigator-assessed acne severity at 8 weeks.

Conclusions:

• Daily at-home treatment with the RBL device is effective for reducing inflammatory and total acne lesions.
• The RBL device demonstrated comparable efficacy to the BL device in most outcomes.
• RBL therapy showed a significant improvement in overall acne severity assessment.