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Updated: Mar 28, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Chiral Nanohoops with π-Extended Helicene Units: Synthesis, Crystal Structure, and Chiroptical Properties
Nan Yin1, Xinyu Zhang1, Pengwei Fang1
1Key Laboratory of Precision and Intelligent Chemistry, Hefei National Research Center for Physical Sciences at the Microscale, Department of Materials Science and Engineering, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, P. R. China.
Abstract:
Herein, we report the synthesis, structural characterization, and physical properties of two helicene-embedded chiral nanohoop enantiomers, [n]cycloparaphenylene-(π-extended [5]helicene) [n]CPP-E5H (n = 7 and 8). Single-crystal X-ray diffraction analysis unambiguously confirms the well-defined hoop-shaped architecture of [7]CPP-E5H, wherein the incorporated helicene adopts a twisted conformation. The enantiomers of [7-8]CPP-E5H, corresponding to (P)- and (M)-helical configurations, were successfully resolved via high-performance liquid chromatography. Their chiroptical properties were studied using circular dichroism, circularly polarized luminescence spectroscopy, and theoretical calculations.
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