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Related Concept Videos

Pericarditis I: Introduction01:22

Pericarditis I: Introduction

625
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
625
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

525
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
525

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Perigraftitis, an independent biologic complication associated with implants placed in grafted bone.

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Related Experiment Video

Updated: Mar 28, 2026

A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
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Clinical, Radiographic, and Histopathologic Features of Human Perigraftitis.

Jonathan H Do1,2, Charles M Cobb3, John T Shen4,5

  • 1Private Practice, San Diego, California, USA.

Journal of Esthetic and Restorative Dentistry : Official Publication of the American Academy of Esthetic Dentistry ... [Et Al.]
|March 27, 2026
PubMed
Summary
This summary is machine-generated.

Perigraftitis, a complication of dental implants in grafted bone, stems from microbial colonization of the graft. Management involves removing infected grafted bone and inflamed tissue.

Keywords:
actinomycosisallograftsamoebabone graftsdental implantsperi‐implantitisxenograft

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Area of Science:

  • Dental implantology
  • Biomaterials science
  • Oral pathology

Background:

  • Perigraftitis is a distinct biologic complication affecting dental implants placed in grafted bone.
  • It differs from peri-implant mucositis and peri-implantitis.
  • This study details the clinical, radiographic, and histopathologic characteristics of perigraftitis.

Purpose of the Study:

  • To further characterize the clinical, radiographic, and histopathologic features of perigraftitis.
  • To understand the etiology and pathology of this complication.
  • To inform management strategies for perigraftitis.

Main Methods:

  • Case series involving three patients with perigraftitis.
  • Surgical debridement of implant fixture and surrounding defect.
  • Histopathologic examination of tissue fragments, including reexamination of prior cases.

Main Results:

  • Clinical signs of inflammation observed around implants in grafted bone.
  • Radiographic evidence of radiolucent defects centered on grafted bone, not the implant.
  • Histopathology revealed microbial aggregates and inflammatory cells within grafted bone, irrespective of graft type.

Conclusions:

  • Perigraftitis originates from microbial colonization of grafted bone.
  • It is not specific to any particular graft material.
  • Management necessitates complete removal of infected grafted bone and associated inflammatory tissue.