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An Experimental Platform to Study the Closed-loop Performance of Brain-machine Interfaces
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A Cloud-Aware Scalable Architecture for Distributed Edge-Enabled BCI Biosensor System
Sayantan Ghosh1,2, Raghavan Bhuvanakantham3,4, Padmanabhan Sindhujaa5
1Department of Biophysics and Radiation Biology, Semmelweis University, 1085 Budapest, Hungary.
Biosensors
|March 27, 2026
Summary
This study introduces a cloud-aware architecture for Brain-Computer Interface (BCI) biosensors, enabling real-time monitoring and edge AI processing. The system demonstrates scalable, energy-efficient data handling for advanced BCI applications.
Area of Science:
- Neuroscience
- Computer Science
- Biomedical Engineering
Background:
- Existing Brain-Computer Interface (BCI) biosensors struggle with scalability, latency, and cloud integration.
- Continuous neural activity monitoring requires robust and efficient data processing frameworks.
Purpose of the Study:
- To develop and validate a cloud-aware, real-time cognitive grid architecture for multimodal BCI biosensors.
- To integrate edge-resident TinyML (Tiny Machine Learning) with cloud infrastructure for enhanced BCI data analytics.
Main Methods:
- A physical prototype integrating BioAmp EXG Pill, RP2040 microcontroller, and environmental sensors was developed.
- A tiered data pipeline (SD card, Redis, PostgreSQL, AWS S3) managed data flow from acquisition to archival.
- Edge-resident TinyML enabled on-device feature extraction and inference, communicating via Wi-Fi/4G.
Main Results:
- The system achieved consistent edge-level inference with bounded latency and packet loss below 5%.
- Cloud-assisted analytics showed variable delays typical of cellular networks and serverless computing.
- Hybrid deployment strategies facilitated cost-efficient validation while maintaining architectural integrity.
Conclusions:
- The developed framework is scalable, modular, and energy-efficient, supporting advanced analytics for translational BCI applications.
- The architecture effectively combines edge-resident TinyML inference with cloud-based machine learning workflows.
- This work lays the foundation for future BCI research and development with improved data handling capabilities.
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