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Community-acquired pulmonary infection caused by Bordetella hinzii: An under-recognized pathogen
Lara Vasconcelos1, Isabel Gonçalves2, Gabriela Jorge da Silva3
1Faculty of Pharmacy of University of Coimbra, University of Coimbra 3000-458, Coimbra, Portugal.
Introduction:
Bordetella hinzii is an emerging Gram-negative pathogen increasingly recognized in humans, especially in patients with chronic lung disease.
Patients And Methods:
A 70-year-old woman with a single lung and recurrent fungal infections presented with progressive respiratory symptoms. Sputum samples were analyzed, and identification was attempted using routine automated systems and confirmed with MALDI-TOF mass spectrometry. Antimicrobial susceptibility was assessed based on MIC determination, current EUCAST guidance for organisms lacking species-specific breakpoints, and comparison with previously reported data.
Results:
The isolate was multidrug-resistant, susceptible only to meropenem. The patient improved after a 14-day course of intravenous meropenem. Routine automated systems failed to identify the pathogen.
Conclusion:
This case highlights the under-recognition of B. hinzii in clinical laboratories and the importance of advanced diagnostic methods and surveillance in vulnerable populations.
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