CT-guided PCI: From diagnosis to treatment planning
Hirofumi Ohashi1, Atomu Tajima1, Koshiro Sakai2
1Department of Cardiology, Aichi Medical University, Aichi, Japan.
Journal of Cardiology
|March 27, 2026
Summary
Computed tomography-guided percutaneous coronary intervention (CT-guided PCI) uses coronary CT angiography (CCTA) for detailed lesion assessment and personalized treatment planning. This approach transforms CCTA into a crucial tool for precision PCI, moving beyond simple diagnosis.
Area of Science:
- Cardiovascular Imaging
- Interventional Cardiology
- Medical Technology
Background:
- Coronary CT angiography (CCTA) traditionally serves a diagnostic role.
- Percutaneous coronary intervention (PCI) planning can benefit from integrated imaging and physiological data.
- Existing PCI strategies may be enhanced by pre-procedural, detailed lesion characterization.
Purpose of the Study:
- To review the concept, workflow, and clinical applications of CT-guided PCI.
- To highlight the evolution of CCTA from a diagnostic tool to a procedural planning platform.
- To discuss the integration of morphological and physiological data for individualized PCI strategies.
Main Methods:
- Integration of morphological and physiological information from CCTA.
- Utilization of advances in myocardial mass quantification and CT-derived physiology.
- Application of three-dimensional co-registration for enhanced procedural relevance.
- Exploration of emerging technologies like photon-counting CT.
Main Results:
- CCTA provides comprehensive lesion understanding for individualized revascularization.
- CT-guided PCI enhances procedural planning and decision-making.
- Ongoing trials and registries are actively evaluating the clinical utility of CT-guided PCI.
Conclusions:
- CT-guided PCI represents a paradigm shift, leveraging CCTA for precision planning.
- Innovations are transforming CCTA into a central platform for contemporary PCI.
- The transition from diagnosis to comprehensive procedural design is underway, improving PCI strategies.
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