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A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis

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Published on: May 10, 2022

Psilocybin Treatment as an Adjunct to Cognitive Behavioral Therapy for Eating Disorders: Therapeutic Rationale &

Elena Koning¹, Susan Gamberg^1,2, Aaron Keshen^1,2

¹Department of Psychiatry, Dalhousie University, Halifax, NS B3H 2E2, Canada.

Behavioral Sciences (Basel, Switzerland)

|March 28, 2026

Summary

Psilocybin treatment may enhance cognitive-behavioral therapy for eating disorders (CBT-ED) by improving patient engagement and outcomes. This approach could reduce dropout rates and improve remission in challenging eating disorder cases.

Keywords:

eating disorders psilocybin psychedelic treatment psychotherapy

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Control of Eating Behavior Using a Novel Feedback System

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Published on: May 8, 2018

Area of Science:

Psychiatry and Neuroscience
Clinical Psychology

Background:

Eating disorders (EDs) present significant treatment challenges, marked by high dropout and low remission rates with standard cognitive-behavioral therapy for EDs (CBT-ED).
Existing treatments for EDs often fall short, necessitating novel therapeutic strategies to improve patient outcomes.

Purpose of the Study:

To review the theoretical evidence supporting the integration of psilocybin treatment (PT) with CBT-ED.
To propose a concurrent intervention protocol for PT/CBT-ED.
To outline clinical and research considerations for evaluating the feasibility, safety, and efficacy of this combined approach.

Main Methods:

This study is a narrative review consolidating theoretical evidence.
It proposes a framework for a concurrent psilocybin treatment and CBT-ED protocol.
It identifies key considerations for future clinical trials.

Main Results:

Psilocybin treatment (PT) exhibits potential neurobiological, psychological, and experiential effects (e.g., antidepressant, neuroplasticity, emotional openness).
These effects are hypothesized to enhance psychotherapeutic engagement, reduce dropout rates, and improve clinical outcomes in CBT-ED.
This review provides the foundational theoretical evidence for combining PT with CBT-ED.

Conclusions:

Integrating psilocybin treatment with CBT-ED offers a promising avenue to improve treatment outcomes for eating disorders.
Further empirical research is crucial to validate the feasibility, safety, and efficacy of this combined therapeutic model.
This innovative approach has the potential to significantly advance the treatment of EDs and the broader application of psychedelics in psychotherapy.