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Dialogues in Immunity: The Interplay Between Neutrophils and Macrophages.
Eduardo Anitua1,2, María Troya1,2, Mohammad H Alkhraisat1,2,3
1BTI-Biotechnology Institute, 01007 Vitoria, Spain.
Biomedicines
|March 28, 2026
Summary
Neutrophil and macrophage cooperation is vital for innate immunity but dysregulation causes chronic inflammation. Precision strategies are needed to modulate their functions, especially during aging, to restore immune balance.
Area of Science:
- Immunology
- Cell Biology
Background:
- Neutrophils and macrophages are key innate immune cells with distinct, complementary roles.
- Their dysregulated cooperation can lead to chronic inflammation and autoimmune diseases.
- Aging impairs these cells, contributing to inflammaging and immune dysfunction.
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