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Updated: Jun 13, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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BRAF Mutations in Myeloid Neoplasms: Prevalence, Co-Mutation Landscape, and Clinical Outcomes-A Comprehensive Review

Shehab F Mohamed1, Ali Mohamed2, Mohamed Fawzi Mudarres3

  • 1Department of Hematology, National Center for Cancer Care and Research (NCCCR), Hamad Medical Corporation, Doha 3050, Qatar.

Biomedicines
|March 28, 2026
PubMed
Summary

BRAF mutations are rare in myeloid neoplasms, often occurring with other genetic changes. While targeted therapies show some response, durable clearance remains a challenge, necessitating further research.

Keywords:
BRAFMAPK pathwayacute myeloid leukemiachronic myelomonocytic leukemiamolecular geneticsmyeloid neoplasmstargeted therapytherapy-related AML

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