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Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

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Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
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Tattoo-Associated Sarcoid-like Uveitis: A Multicenter Registry Study.

Ryoji Yanai1, Yuko Misaki1, Mariko Egawa1

  • 1Department of Ophthalmology, Tokushima University Hospital, Tokushima 770-8503, Japan.

Biomedicines
|March 28, 2026
PubMed
Summary
This summary is machine-generated.

Tattoo-associated sarcoid-like uveitis frequently recurs and can lead to uveitic glaucoma. Close monitoring and systemic evaluation are recommended for patients with this condition.

Keywords:
glaucomaregistrysarcoidosistattoouveitis

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Area of Science:

  • Ophthalmology
  • Immunology
  • Dermatology

Background:

  • Limited data exists on tattoo-associated sarcoid-like uveitis.
  • This study characterizes clinical features and outcomes.

Purpose of the Study:

  • To investigate the clinical presentation and prognosis of tattoo-associated sarcoid-like uveitis.
  • To identify key management strategies and potential complications.

Main Methods:

  • Retrospective review of 10 patients with tattoo-associated sarcoid-like uveitis from a multicenter registry.
  • Data collected included demographics, treatments, visual acuity, recurrence, glaucoma, extraocular involvement, and histology.
  • Follow-up averaged 20 months.

Main Results:

  • Seven out of ten patients were male, with a mean age of 35.1 years.
  • All patients had bilateral ocular involvement; 50% had histologic confirmation at the tattoo site.
  • Uveitis recurrence occurred in 70%, and 80% required glaucoma/intraocular pressure-lowering therapy. Extraocular inflammation affected skin/tattoos in 70%.

Conclusions:

  • Tattoo-associated sarcoid-like uveitis typically presents a chronic course with high recurrence rates.
  • Uveitic glaucoma is a common complication, necessitating proactive management.
  • Regular ophthalmic surveillance and systemic assessment are crucial for affected individuals.