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Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
Published on: June 30, 2023
Clinical and Comorbidity-Related Factors Associated with Health-Related Quality of Life in Patients with Heart
Teodora-Gabriela Alexescu1, Mara-Ioana Somesfalean2, Mirela-Georgiana Perne1
14th Medical Discipline, Department of Internal Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania.
Insights
This study found that factors like older age and obesity negatively impact heart failure patients
Area of Science:
- Cardiology
- Internal Medicine
- Quality of Life Research
Background:
- Heart failure significantly impacts patients' prognosis and quality of life, affecting physical and psychological well-being.
- It leads to numerous daily life limitations for individuals diagnosed with this prevalent condition.
Purpose of the Study:
- To identify factors influencing the quality of life in heart failure patients.
- Investigate associations between disease severity, comorbidities, and living conditions impacting patient well-being.
Main Methods:
- Cross-sectional observational study conducted in Romania (2024-2025).
- Included 122 hospitalized heart failure patients (mean age 67.9 years, 62% women).
- Utilized the Minnesota Living with Heart Failure Questionnaire for self-assessment.
Main Results:
- Positive associations with quality of life: female sex, atrial fibrillation with electrostimulated rhythm, type 2 diabetes, hypertension, hepatitis, chronic gastritis.
- Negative associations with quality of life: advanced age, obesity, higher NYHA class, reduced ejection fraction, valvular heart disease, obstructive sleep apnea, polydiscopathy, hyperthyroidism, hepatic steatosis.
Conclusions:
- Key factors significantly influence the quality of life in heart failure patients.
- Understanding these factors is crucial for improving patient management and outcomes.
Abstract:
Heart failure is one of the most prevalent conditions worldwide, exerting a substantial impact on both prognosis and quality of life. It affects both psychological and physical domains, leading to multiple limitations in patients' daily lives. Background/Objectives: The primary objective of this study was to identify clear factors related to disease severity, living conditions, and associated comorbidities that may negatively influence the quality of life of patients with heart failure. Methods: This study had a cross-sectional observational design and was conducted between 2024 and 2025 in the Department of Internal Medicine of the CF University Hospital in Cluj-Napoca, Romania. A total of 122 patients (mean age 67.9 ± 9.69 years, 62% women) diagnosed with heart failure, regardless of ejection fraction, and hospitalized in the Internal Medicine department during the study period were included. All participants self-administered the Minnesota Living with Heart Failure Questionnaire. Results: The analysis identified several factors associated with better quality of life, including female sex, atrial fibrillation with electrostimulated heart rhythm, type 2 diabetes mellitus, arterial hypertension, hepatitis, and chronic gastritis. Conversely, several factors were found to have a negative association with quality of life, such as advanced age, obesity, higher New York Heart Association (NYHA) functional class, reduced ejection fraction, valvular heart disease, obstructive sleep apnea syndrome, cervical-thoracic-lumbar polydiscopathy, hyperthyroidism, and hepatic steatosis. Conclusions: These results highlight the importance of key factors associated with quality of life in patients with heart failure.
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