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Updated: Sep 27, 2026

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
Published on: May 13, 2019
Chemotherapy-Induced Right Ventricular Dysfunction
Camil-Horia-Eusebiu Crișan1,2, Anca-Daniela Fărcaș1,3, Andrada-Viorica Pârvu4,5
14th Department of Internal Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Abstract:
The right ventricle has been considered by many clinicians to be the "forgotten chamber" of the heart. In this narrative review of the literature, we aim to examine chemotherapy-induced right ventricular failure. We will discuss the clinical significance of the subject, the effects of chemotherapy on the heart, and why it is crucial to take a closer look at the right ventricle. We will present key aspects of the anatomy and physiology of the right ventricle and how it differs from the left ventricle. Furthermore, this review explains the mechanisms behind chemotherapy-induced right ventricular dysfunction, strategies for assessing the right ventricle, recent advancements in cardiac imaging, available treatment options, and future directions in therapeutic management.
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