Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Glaucoma: Overview01:25

Glaucoma: Overview

1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

11.7K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
11.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unlocking the Functional Potential of <i>Lonicera caerulea</i>: Chemical Profile, Antioxidant, and <i>α</i>-Amylase and <i>α</i>-Glucosidase Inhibitory Activities of Extracts from Ripe, Unripe, and Lactofermented Fruits.

Biomolecules·2026
Same author

Unilateral Idiopathic Foveal Haemorrhage in a Young Female Adult.

Case reports in ophthalmological medicine·2026
Same author

Effect of tipiracil hydrochloride, thymidine phosphorylase inhibitor, on the ischemia/reperfusion injury of brain tissue in rats.

Scientific reports·2026
Same author

Isoxazole derivatives as multi-target agents: virucidal, antibacterial, and antiproliferative effects on skin cancer cells.

Pharmacological reports : PR·2026
Same author

Serum Chemerin Levels in Polish Women with PCOS-Phenotype D.

Journal of clinical medicine·2026
Same author

Poisoning with Thyroid Hormones Used Illegally-Systematic Review.

Pharmaceuticals (Basel, Switzerland)·2025

Related Experiment Video

Updated: Mar 29, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
12:00

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro

Published on: July 5, 2017

20.1K

Standardized Berry Extract Improves Selected Visual Function Outcomes in Presbyopia: A Randomized, Double-Blind,

Dorota Szumny1,2, Alicja Zofia Kucharska3, Karolina Czajor2,4

  • 1Department of Pharmacology, Faculty of Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.

Nutrients
|March 28, 2026
PubMed
Summary

A berry extract (AKB) showed modest improvements in near vision and related biomarkers in adults over 50. Further research is needed to confirm these preliminary findings on visual function and ocular homeostasis.

Keywords:
TRPV4anthocyaninscrystallinsiridoidsoptical coherence tomographypresbyopiavisual evoked potentialsvisual function

More Related Videos

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia
06:19

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Published on: September 27, 2024

631
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

10.9K

Related Experiment Videos

Last Updated: Mar 29, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
12:00

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro

Published on: July 5, 2017

20.1K
Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia
06:19

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Published on: September 27, 2024

631
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

10.9K

Area of Science:

  • Ophthalmology
  • Nutritional Science
  • Pharmacology

Background:

  • Presbyopia, an age-related vision decline, is linked to lens stiffening and neuroretinal changes.
  • Limited evidence exists on berry phytochemicals' effects on presbyopia.
  • Aronia melanocarpa, Lonicera caerulea, and Vaccinium myrtillus are sources of beneficial compounds.

Purpose of the Study:

  • To investigate the effects of a standardized berry extract (AKB) on visual performance.
  • To assess AKB's influence on circulating biomarkers related to ocular homeostasis.
  • To explore potential benefits for age-related near vision decline.

Main Methods:

  • Randomized, double-blind, placebo-controlled, two-period crossover trial.
  • 23 adults over 50 years old participated.
  • Intervention involved AKB (400 mg twice daily) or placebo for 6 weeks with a 5-week washout.

Main Results:

  • AKB improved near contrast sensitivity and visual-field parameters compared to placebo.
  • Favorable changes observed in VEP and OCT readouts.
  • AKB modulated specific circulating biomarkers (αA-/αB-crystallin, ALDH1A1, TRPV4) but not systemic antioxidant enzymes or AGEs.

Conclusions:

  • Short-term AKB supplementation demonstrated modest, exploratory effects on visual function and biomarkers.
  • Findings suggest potential, but preliminary, benefits for ocular homeostasis.
  • Larger, longer-term studies are required to confirm clinical relevance and elucidate mechanisms.