Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

2.2K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
2.2K
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

4.1K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
4.1K
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

3.1K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
3.1K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

5.0K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
5.0K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.4K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.4K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

4.1K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
4.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cancer History and Subjective Sleepiness in Obstructive Sleep Apnea: A Real-World Observational Study.

Journal of clinical medicine·2026
Same author

Sex-dependent transcriptional and epigenetic regulation of neutrophil inflammatory programs in COPD.

Frontiers in immunology·2026
Same author

Cumulative nocturnal hypoxemia, but not apnea-hypopnea index, is independently associated with vertebral fracture burden in obstructive sleep apnea.

European journal of internal medicine·2026
Same author

Prevalence and incidence of pressure injury in adult patients receiving non-invasive ventilation for acute respiratory failure: a systematic review and meta-analysis protocol.

JBI evidence synthesis·2026
Same author

Monographic Issue on New Concepts in Acute Exacerbations of COPD.

Seminars in respiratory and critical care medicine·2026
Same author

Clinical significance of head CT scan in patients admitted to the emergency department with mild head trauma.

Internal and emergency medicine·2026

Related Experiment Video

Updated: Mar 29, 2026

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD
04:03

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

Published on: September 27, 2024

1.6K

The Evolving Landscape of COPD Typization.

Alberto Fantin1,2, Nadia Castaldo1, Giulia Sartori2

  • 1Department of Pulmonology, S. Maria della Misericordia University Hospital, 33100 Udine, Italy.

Medicina (Kaunas, Lithuania)
|March 28, 2026
PubMed
Summary
This summary is machine-generated.

Chronic obstructive pulmonary disease (COPD) is complex. New methods like biomarkers and AI offer personalized treatments beyond traditional diagnoses for better COPD care.

Keywords:
COPDendotypeeosinophilomicsphenotype

More Related Videos

Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections
06:22

Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections

Published on: September 19, 2025

642
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

11.7K

Related Experiment Videos

Last Updated: Mar 29, 2026

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD
04:03

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

Published on: September 27, 2024

1.6K
Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections
06:22

Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections

Published on: September 19, 2025

642
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

11.7K

Area of Science:

  • Pulmonary Medicine
  • Genomics
  • Medical Imaging

Background:

  • Chronic obstructive pulmonary disease (COPD) presents significant global health challenges due to its heterogeneity.
  • Current diagnostic methods based on spirometry and broad phenotypes inadequately address the molecular complexity for precision medicine.

Purpose of the Study:

  • To review advancements in COPD characterization beyond traditional diagnostics.
  • To explore the integration of biomarkers, quantitative imaging, and multi-omics for personalized COPD management.

Main Methods:

  • Narrative review synthesizing current literature on COPD characterization.
  • Analysis of biomarker validation, quantitative imaging, multi-omics, and AI applications.
  • Exploration of the proposed GETomics framework (Genetics, Environment, and Time).

Main Results:

  • Clinical validation of biologics targeting type 2 inflammation signifies a move towards treatable traits.
  • Artificial intelligence and deep learning show promise in improving radiological and body composition analysis.
  • Integration of diverse data sources is crucial for advanced COPD phenotyping.

Conclusions:

  • A paradigm shift is occurring from generic COPD management to precision medicine targeting specific traits.
  • The proposed GETomics framework offers a foundation for future personalized COPD care.
  • Advanced technologies are essential for overcoming limitations of traditional COPD classification systems.