Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Physiology of Smell and Olfactory Pathway

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

FSCL-BC: Federated supervised contrastive learning for breast cancer diagnosis with high sensitivity.

Computer methods and programs in biomedicine·2026

Same author

Poly(lactic acid-<i>co</i>-oxacyclohexadecenlactone) (PLH): A Bio-Based Substrate for Flexible Printed Electronic Devices.

ACS applied materials & interfaces·2026

Same author

Unsupervised utility evaluation of text anonymization methods via neural language models.

Neural networks : the official journal of the International Neural Network Society·2026

Same author

Adhesion-controlled mechanics of the glial niche regulate neural stem cell proliferative potential.

Developmental cell·2026

Same author

Controlling MoS<sub>2</sub> Nanosheet Size and Network Conductivity through Alkylammonium Ion Selection.

ACS applied materials & interfaces·2026

Same author

EpiCure (Epithelial Curation): a versatile and handy tool for curation of epithelial segmentation.

bioRxiv : the preprint server for biology·2026

Same journal

Computational protocol for modeling supported nanoparticle catalysts with strong metal-support interactions.

STAR protocols·2026

Same journal

Protocol for genomic mapping of chromatin targets using high-throughput CUT&RUN.

STAR protocols·2026

Same journal

A protocol for noninvasive quantification of dietary fat absorption in mice.

STAR protocols·2026

Same journal

Protocol for an AlCl<sub>3</sub>-induced Alzheimer's model in zebrafish larvae with optimized pH and behavioral assessment.

STAR protocols·2026

Same journal

Protocol for live cell barcoding and immunophenotyping of human hematological malignancies using cytometry by time of flight.

STAR protocols·2026

Same journal

Generating drug resistance models in human and murine cancer cell lines and assessing cross-resistance to chemotherapeutics and KRAS inhibitors.

STAR protocols·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 30, 2026

The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo

The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo

Published on: October 30, 2014

Protocol to explore olfactory placode morphogenesis using an agent-based model.

Vincent Demont¹, Gaëlle Letort², David Sanchez³

¹Unité de Biologie Moléculaire, Cellulaire et du Développement (MCD, UMR5077), Centre de Biologie Intégrative (CBI, FR 3743), Université de Toulouse, CNRS, UPS, Toulouse 31062, France.

|March 28, 2026

Summary

This summary is machine-generated.

Mathematical modeling helps test developmental hypotheses. This study uses modeling to explore how chemotactic source distribution affects olfactory rosette formation in zebrafish development, providing code for analysis.

Keywords:

Computer sciences Developmental biology Model Organisms

More Related Videos

An Explant System for Time-Lapse Imaging Studies of Olfactory Circuit Assembly in Drosophila

An Explant System for Time-Lapse Imaging Studies of Olfactory Circuit Assembly in Drosophila

Published on: October 13, 2021

Functional Evaluation of Olfactory Pathways in Living Xenopus Tadpoles

Functional Evaluation of Olfactory Pathways in Living Xenopus Tadpoles

Published on: December 11, 2018

Related Experiment Videos

Last Updated: Mar 30, 2026

The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo

The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo

Published on: October 30, 2014

An Explant System for Time-Lapse Imaging Studies of Olfactory Circuit Assembly in Drosophila

An Explant System for Time-Lapse Imaging Studies of Olfactory Circuit Assembly in Drosophila

Published on: October 13, 2021

Functional Evaluation of Olfactory Pathways in Living Xenopus Tadpoles

Functional Evaluation of Olfactory Pathways in Living Xenopus Tadpoles

Published on: December 11, 2018

Area of Science:

Developmental Biology
Computational Biology
Zebrafish Models

Background:

Mathematical modeling is crucial for testing developmental hypotheses.
Understanding cell signaling pathways is key to developmental processes.
Chemotaxis plays a significant role in guiding cell migration during development.

Purpose of the Study:

To present a protocol for investigating chemotactic influences on zebrafish olfactory rosette formation.
To explore how variations in chemotactic source distribution impact bilateral rosette development.
To provide a computational framework for analyzing chemotaxis in developmental contexts.

Main Methods:

Utilizing mathematical modeling to simulate developmental processes.
Implementing a protocol to set up parameters for chemotaxis simulations.
Modifying and testing different chemotaxis force parameters.
Providing code for installation, execution, and visualization of results.

Main Results:

The protocol allows for the investigation of chemotactic source distribution effects.
Simulations can reveal how chemotactic forces influence rosette formation.
The provided code enables visualization of simulation outcomes.

Conclusions:

This protocol offers a method to assess developmental hypotheses using mathematical modeling.
Variations in chemotaxis significantly influence olfactory rosette formation in zebrafish.
The computational approach facilitates deeper understanding of cell guidance mechanisms.