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Exercise increases transglutaminase 2 expression in skeletal muscle

Tomoya Kitakaze1,2, Manami Dokan1, Yuki Kishi2

  • 1Department of Applied Biological Chemistry, Graduate School of Agriculture, Osaka Metropolitan University, Sakai, Osaka, Japan.

Bioscience, Biotechnology, and Biochemistry
|March 28, 2026
PubMed

Keywords:
ATF-6αPGC-1α4exerciseskeletal muscletransglutaminase 2

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Exercise and Muscle Performance01:27

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...