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Surgical Principles and Approaches to Gingivobuccal Cancers
Collin W Enfinger1, Daniel P Caruso1, Marina Morante Silva1
1Department of Oral & Maxillofacial Surgery, University of Florida - Jacksonville, Jacksonville, FL, USA.
Oral and Maxillofacial Surgery Clinics of North America
|March 28, 2026
Summary
Surgical management of gingivobuccal cancers requires careful planning due to complex anatomy. Achieving negative surgical margins is crucial for local control, with advanced techniques aiding this goal.
Area of Science:
- Oncology
- Surgical Oncology
- Oral Surgery
Background:
- Gingivobuccal cancers are a challenging subset of oral cavity cancer.
- These tumors often invade critical structures, exhibit submucosal spread, and involve bone.
Purpose of the Study:
- To review general principles and surgical approaches for gingivobuccal cancers.
- To highlight the importance of achieving negative surgical margins for local control.
Main Methods:
- Review of existing literature on surgical management of gingivobuccal cancers.
- Discussion of en bloc resection as the primary management strategy.
- Exploration of individualized surgical approaches based on tumor characteristics.
Main Results:
- En bloc resection is the cornerstone of treatment for gingivobuccal cancers.
- Surgical approach must be tailored to tumor location, stage, and invasion depth.
- Negative surgical margins are critical for successful local tumor control.
Conclusions:
- Effective surgical management of gingivobuccal cancers necessitates a thorough understanding of anatomy and tumor behavior.
- Individualized surgical strategies and achieving negative margins are key to improving outcomes.
- Emerging technologies like dynamic margin assessment and imaging guidance show promise for enhancing surgical precision.

