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Updated: Mar 31, 2026

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time
Published on: March 11, 2021
A dual-site fluorescent probe for tracing the interaction between ATP and NE in neuroinflammation
Na Zhou1, Changsheng Guo1, Fangjun Huo2
1Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Biomedical and Health Laboratory in Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. yincx@sxu.edu.cn.
Abstract:
A dual-site fluorescent probe without cross-coloring visualizes the exocytosis of ATP and NE in a neuroinflammatory model, revealing that ATP, released as a co-transmitter, promotes NE exocytosis, thus providing a new target for early intervention in related diseases.
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