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Surgical Reconstruction of Ulcers in Chronic Granulomatous Disease
Lucas A Dvoracek1,2, Winston R Owens1,2, Vamsi C Mohan1,2
1From the Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.
Abstract:
Chronic granulomatous disease can affect multiple organ systems and is associated with poor wound healing, which may preclude a patient from undergoing a bone marrow transplant. We present a patient with chronic granulomatous disease and extensive nonhealing full-thickness wounds who was successfully treated surgically with split-thickness skin grafts and spray-on autologous skin cell suspension. This treatment paradigm may be useful for other patients with immunologic dysfunction and chronic wounds.
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