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Transaortic Transcatheter Aortic Valve Replacement With Bicuspid Aortic Valve Stenosis and Circumflex Aortic Arch

Merrina Lan1, Matthew C Henn2, Konstantinos Dean Boudoulas3

  • 1The Ohio State University College of Medicine Columbus Ohio USA.

Clinical Case Reports
|March 30, 2026
PubMed

Insights

Transcatheter aortic valve replacement (TAVR) was successfully performed using a transaortic approach in a patient with a rare circumflex aortic arch anomaly. This represents the first documented case of TAVR in this specific anatomical variation.

Area of Science:

  • Cardiology
  • Congenital Heart Disease
  • Interventional Cardiology

Background:

  • Circumflex aortic arch is a rare congenital anomaly affecting aortic arch anatomy.
  • Management of aortic valve disease in patients with complex aortic arch anomalies presents unique challenges.

Purpose of the Study:

  • To describe the first case of transcatheter aortic valve replacement (TAVR) in a patient with a circumflex aortic arch.
  • To illustrate the feasibility and approach for TAVR in this rare anatomical variant.

Main Methods:

  • Transcatheter aortic valve replacement (TAVR) procedure.
  • Transaortic access technique.
  • Management of circumflex aortic arch anatomy during TAVR.

Main Results:

  • Successful implantation of a transcatheter aortic valve.
  • Favorable procedural outcome without major complications.
  • Demonstration of a viable transaortic approach for TAVR in circumflex aortic arch.

Conclusions:

  • Transcatheter aortic valve replacement (TAVR) is feasible in patients with circumflex aortic arch.
  • The transaortic approach can be utilized for TAVR in this rare anomaly.
  • This case expands the understanding of TAVR in complex congenital aortic arch variations.

Keywords:
TAVRcircumflex aortic archcongenital heart diseasetranscatheter aortic valve replacement

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