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Updated: Mar 31, 2026

Endotracheal Intubation Using a Flexible Intubation Endoscope as a Standardized Model for Safe Airway Management in Swine
Published on: August 25, 2022
AI-assisted videolaryngoscopy improves intubation success: results from a randomized simulation trial
Ariadna Comaniciu1, David Schurter2, Ajsi Kanapari3,4
1Division of Anaesthesia, Schulthess Klinik, Lengghalde 2, 8008, Zürich, Switzerland.
AI-powered larynGuide software improved tracheal intubation success rates during simulated airway management. This artificial intelligence tool enhances C-MAC video laryngoscopy efficacy, particularly for experienced professionals.
Area of Science:
- Anesthesiology
- Medical technology
- Artificial intelligence in medicine
Background:
- Video laryngoscopy is crucial for airway management but faces challenges like depth perception loss and cognitive load.
- Existing video laryngoscopes may not succeed in all airway scenarios.
Purpose of the Study:
- To evaluate the efficacy of larynGuide, an AI software integrated with C-MAC video laryngoscopy, in improving tracheal intubation success rates.
- To assess the impact of AI on both easy and difficult airway simulations.
Main Methods:
- A prospective, randomized, 2x2 crossover, simulation-based study involving 74 medical professionals.
- Participants performed tracheal intubations with and without larynGuide AI overlay on a C-MAC video laryngoscope.
- Primary outcome: first attempt success rate. Secondary outcomes: overall success, intubation time, performance scores, dental injury incidence.
Main Results:
- The overall first attempt success rate was 89% with larynGuide versus 85% with standard C-MAC, with 72% higher odds of success using larynGuide (OR=1.72, p=0.022).
- The benefit was more pronounced in experienced participants (OR=3.37, p=0.016).
- Time to intubation was longer with larynGuide (29s vs 23s, p<0.01), and dental injury incidence was lower (22% vs 27%, p=0.095).
Conclusions:
- larynGuide AI software significantly improved tracheal intubation success rates in a simulated environment compared to standard C-MAC videolaryngoscopy.
- AI shows potential for enhancing airway management, with greater benefits observed in experienced professionals.
- Further clinical studies are warranted to confirm these findings and support wider clinical adoption.
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