Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Letter: Further Considerations on the Clinical Use of the Scottish Inflammatory Prognostic Score in STEMI No-Reflow Prediction.

Angiology·2026

Same author

Impact of Frontline Treatment Strategies on Outcomes in Patients With Acute Myeloid Leukemia, Myelodysplasia-Related.

Cancer reports (Hoboken, N.J.)·2026

Same author

Theoretical exploration of NIR-II circularly polarized luminescence in open-shell boron-embedded pyrene-naphthalene helicenes.

Physical chemistry chemical physics : PCCP·2026

Same author

Maternal exposure to polystyrene nanoplastics triggers ovarian injury in mice offspring: Ferroptosis mediated by the HIF-1α/HO-1 pathway.

Reproductive toxicology (Elmsford, N.Y.)·2026

Same author

An Efficient Pharmacogenomic Assay for Psychotropic Drugs by Multiplex Fluorescence Melting Curve Analysis.

Drug design, development and therapy·2026

Same author

The immune landscape of melanoma microenvironmental crosstalk.

Frontiers in immunology·2026

Same journal

Informed-Exploration Reinforcement Learning for Automated Virtual Coronary Intervention Planning.

IEEE transactions on medical imaging·2026

Same journal

4D Reconstruction of Fetal Left Ventricle from Echocardiography via 2.5D Radial Segmentation and Graph-Fourier Reconstruction.

IEEE transactions on medical imaging·2026

Same journal

Generalised Medical Phrase Grounding.

IEEE transactions on medical imaging·2026

Same journal

EndoLRMGS: Combining Large Reconstruction Modelling and Gaussian Splatting for Complete Endoscopic Scene Reconstruction.

IEEE transactions on medical imaging·2026

Same journal

A Neural-Analytical Fusion Scatter Correction Method for Multi-Source CT Using Equivalent High-Order Scatter.

IEEE transactions on medical imaging·2026

Same journal

SynReEM: Synapse Reconstruction via Instance Structure Encoding in Anisotropic Electron Microscopic Volumes.

IEEE transactions on medical imaging·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 1, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Insights from particle simulations for diffusion MRI microstructure studies.

Viktor Vegh, Qianqian Yang, Megan Farquhar

IEEE Transactions on Medical Imaging

|March 30, 2026

Summary

This summary is machine-generated.

Simulations reveal how water diffusion in tissue is affected by cell size and exchange between compartments. This research enhances understanding of diffusion MRI models for tissue microstructure imaging.

More Related Videos

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Diffusion Imaging in the Rat Cervical Spinal Cord

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

Related Experiment Videos

Last Updated: Apr 1, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Diffusion Imaging in the Rat Cervical Spinal Cord

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

Area of Science:

Biomedical Imaging
Biophysics
Computational Biology

Background:

Diffusion MRI quantifies water diffusion to study tissue microstructure.
Existing analytical models for water diffusion in tissue have limitations in understanding and relevance.
Soft tissue studies can greatly benefit from diffusion MRI's microstructure insights at millimeter scales.

Purpose of the Study:

To provide insights into hindered and restricted diffusion compartments using simulations.
To investigate how inter-compartment exchange affects the diffusion process.
To improve understanding of factors influencing temporal dependence of diffusion and kurtosis.

Main Methods:

Performed simulations of water diffusion in simplified tissue models.
Considered distinct cases for modeled spherical cell size and diffusivity.
Applied the theory of diffusional retardation to describe observations.

Main Results:

Simulations provided insights into hindered and restricted diffusion compartments.
The effect of inter-compartment exchange on diffusion was characterized.
Observations were described using the theory of diffusional retardation.

Conclusions:

The findings may lead to novel approaches for tissue microstructure imaging.
Improved understanding of factors influencing temporal diffusion dependence and kurtosis is expected.
This work contributes to refining diffusion MRI models for biological tissues.