Urethral Diverticulum Mimicking Malignancy on FDG PET/CT.

Area of Science:

• Urology
• Radiology
• Oncology

Background:

• Female urethral diverticulum (FUD) is a rare condition.
• Diagnosis can be challenging due to its uncommon nature.

Purpose of the Study:

• To highlight the importance of considering FUD in the differential diagnosis of FDG-avid periurethral lesions.
• To emphasize the role of correlating imaging findings with patient history.

Main Methods:

• Case report of an 80-year-old woman.
• Utilized FDG PET/CT for cancer restaging.
• Correlated PET/CT findings with prior pelvic MRI.

Main Results:

• FDG PET/CT revealed a suspicious hypodense, FDG-avid periurethral lesion.
• The lesion was confirmed as a urethral diverticulum, previously detected on MRI.
• The finding highlights potential for misinterpretation as malignancy.

Conclusions:

• Urethral diverticulum should be included in the differential diagnosis of FDG-avid periurethral findings.
• Integrating patient history and cross-sectional imaging aids accurate diagnosis.