Motor Imagery and Action Observation in Breast Cancer Survivors: Protocol for a Randomized Controlled Trial

Area of Science:

• Rehabilitation medicine
• Neurology
• Oncology

Background:

• Breast cancer is a leading global cancer in women, with increasing incidence.
• Survivors often experience persistent physical sequelae like pain, lymphedema, and functional limitations.
• Current treatments for these symptoms have limited effectiveness.

Purpose of the Study:

• To evaluate a combined motor imagery (MI) and action observation (AO) therapy program for breast cancer survivors.
• The program aims to enhance upper limb functionality, mobility, and alleviate pain and lymphedema.

Main Methods:

• A randomized controlled trial involving 108 breast cancer survivors with pain, lymphedema, or reduced strength/mobility.
• Intervention group (54 participants): MI, AO, and mobility exercises.
• Control group (54 participants): mobility exercises alone.

Main Results:

• The study is ongoing, with 80 participants recruited as of manuscript submission.
• Data analysis is pending, with expected results publication in 2026.
• Expected outcomes include improvements in pain, joint range, muscle strength, and lymphedema symptoms.

Conclusions:

• Motor imagery and action observation therapy show potential for improving the quality of life for breast cancer survivors.
• This intervention may positively impact physical and psychological sequelae affecting daily living.