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Updated: Jun 21, 2026

The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
Published on: November 19, 2008
The Weeke Score Is an Easy-to-Teach and Reliable System for Hypoxic-Ischemic Encephalopathy Brain Magnetic Resonance
Jun Li1, Zarina Assis1, Sujith Kumar Reddy Gurram Venkata2
1Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Abstract:
Magnetic resonance imaging (MRI) is the imaging of choice to diagnose brain injury and prognosticate long-term neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy (HIE). Independent scoring from Neuroradiology and Neonatology fellows was obtained for 97 brain MRIs for HIE after teaching. Analysis for reliability was compared against a gold standard of an experienced Neuroradiologist. There was good (intraclass correlation coefficient: 0.87) reliability for the Neonatology fellow and excellent (intraclass correlation coefficient: 0.94) reliability for the Neuroradiology fellow compared with the Neuroradiologist. This suggests that the scoring system used has good interobserver reliability between less experienced readers compared with an experienced reader.

