Related Experiment Video
Updated: Apr 1, 2026

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
Published on: October 2, 2014
Use of low-value cancer care in practices acquired by private equity firms
Aaron P Mitchell1, Miranda B Lam2, Caroline Carlin3
1Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Abstract:
Private equity acquisition of medical practices has been associated with increased prices and use of lucrative treatments. Using Medicare data from 2015 to 2021, we compared the prevalence of low-value cancer treatments between private equity-owned and non-private equity-owned practices. The 5 low-value treatments were (1) granulocyte colony-stimulating factors for low-risk chemotherapy, (2) denosumab for castration-sensitive prostate cancer, (3) nab-paclitaxel for breast or lung cancer, (4) the addition of bevacizumab for ovarian cancer, and (5) biologic agents with biosimilar alternatives. The primary outcome was receipt of a low-value treatment. Comparing patients diagnosed when their oncologist was vs was not practicing at a private equity-owned address, adjusted prevalence differences of low-value treatments were -2.8 percentage points (95% confidence interval [CI] = -5.5 to -0.2) for granulocyte colony-stimulating factors, +3.7 percentage points (95% CI = -7.3 to 14.7) for denosumab, -0.7 percentage points (95% CI = -3.9 to 1.5) for nab-paclitaxel, -6.5 percentage points (95% CI = -12.5 to -0.4) for bevacizumab, and -2.9 percentage points (95% CI = -6.0 to 0.2) for biologics. Overall, private equity ownership was not associated with increased prevalence of low-value cancer treatments.
More Related Videos
06:42Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025
13:24Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
Published on: April 11, 2016
Related Concept Videos
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Issues And Trends In Healthcare Delivery System
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Secondary Healthcare System
Healthcare Agencies I
Ethical Issues
Ethical Concerns in Healthcare:
Healthcare Agencies II
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...