The Newborn With a Suspected Difference of Sex Development.

Area of Science:

• Pediatric Endocrinology
• Neonatology
• Genetics

Background:

• Care for differences of sex development (DSD) is evolving, particularly for newborns.
• A
• social crisis
• can arise with suspected DSD in infants.

Purpose of the Study:

• To present a paradigm for the care of newborns with suspected DSD.
• To emphasize a family-focused, shared decision-making approach.
• To guide neonatal teams in initial management and diagnostic evaluation.

Main Methods:

• Review of current practices and evolving care standards for DSD in neonates.
• Emphasis on a multidisciplinary, family-centered approach.
• Discussion of essential neonatal tasks and long-term care coordination.

Main Results:

• A family-focused, shared decision-making model can de-escalate crisis.
• Neonatal team tasks include monitoring, diagnostics (sex chromosomes, congenital adrenal hyperplasia), and initiating evaluation.
• Surgery is rarely indicated neonatally; counseling should be realistic.

Conclusions:

• Care for newborns with DSD requires a paradigm shift towards family-centered, shared decision-making.
• Multidisciplinary teams and accessible resources are crucial for optimal patient and family support.
• Early diagnostics and appropriate psychosocial support are key components of neonatal DSD management.