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Updated: Apr 2, 2026

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Photoinduced Deacylative Phosphorylation of Unstrained Ketones
Long Zhang1, Jianing Yu1, Xiaoyun Hu1
1Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education, School of Chemistry and Materials Science, South-Central Minzu University, Wuhan 430074, China.
None:
The photoinduced deacylative transformation of ketones represents a powerful strategy for forming chemical bonds and developing innovative reactions. However, its potential application in deacylative phosphorylation remains unexplored. Herein, we report a metal-free, light-driven deacylative phosphorylation of unstrained ketones with diarylchlorophosphines, enabling the efficient synthesis of a wide variety of symmetrical and unsymmetrical tertiary phosphines. This method features mild conditions, operational simplicity, and broad substrate scope.
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