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Radiographic choice for skeletal maturation assessment: a systematic review of Cervical Vertebrae Method and Middle

Angelo Michele Inchingolo1,2, Grazia Marinelli1, Francesca Calò1

  • 1Interdisciplinary Department of Medicine, School of Medicine, University of Bari "Aldo Moro", 70124, Bari, Italy.

Oral Radiology
|April 1, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Artificial IntelligenceCervical vertebral maturationDeep learningPubertal growth spurtSkeletal age

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The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...