Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

9.5K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
9.5K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

677
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
677

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HRRT: hierarchical reinforcement learning for renal replacement therapy decision support.

NPJ digital medicine·2026
Same author

Identifying dynamic antithrombin Ⅲ trajectories to predict clinical outcomes in intra-abdominal sepsis.

Journal of intensive medicine·2026
Same author

Evaluation of the InTempo path set for CyberKnife prostate and lung SBRT: A single-institution experience.

Journal of applied clinical medical physics·2026
Same author

Life cycle cost of communication towers: identification and hierarchical classification of influencing factors.

Scientific reports·2025
Same author

Influence of foam content on mechanical properties and thermal conductivity of ceramsite foam concrete.

Scientific reports·2025
Same author

Evaluating artifact-free four-dimensional computer tomography with 16 cm detector array.

Journal of applied clinical medical physics·2025

Related Experiment Video

Updated: Apr 2, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
12:24

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Published on: July 17, 2012

13.0K

Computed tomography for four-dimensional dose calculation: Effect of detector array length.

Inhwan Yeo1, Qianyi Xu2

  • 1Department of Advanced Radiation and Proton Therapy, Fairfax, Virginia, USA.

Journal of Applied Clinical Medical Physics
|April 1, 2026
PubMed
Summary
This summary is machine-generated.

Four-dimensional computed tomography (4DCT) with 16-cm detectors improves geometrical accuracy for lung cancer treatment planning. This advanced 4DCT ensures reliable 4D dose delivery with intensity-modulated proton therapy (IMPT) plans.

Keywords:
16 cm‐length detector for 4DCT4D doserespiratory artifacts

More Related Videos

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

15.0K
A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
14:19

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

9.0K

Related Experiment Videos

Last Updated: Apr 2, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
12:24

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Published on: July 17, 2012

13.0K
X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

15.0K
A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
14:19

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

9.0K

Area of Science:

  • Medical Imaging
  • Radiation Oncology
  • Computed Tomography

Background:

  • Four-dimensional computed tomography (4DCT) is crucial for radiation therapy planning, enabling motion management.
  • Conventional 4DCT with 4-cm detectors can introduce geometrical errors due to patient movement during scanning.
  • Wider detector arrays (16-cm) in 4DCT offer improved geometrical accuracy by minimizing patient repositioning.

Purpose of the Study:

  • To evaluate the geometrical accuracy and 4D dose delivery of 4DCT using 16-cm detectors compared to conventional 4-cm detectors.
  • To assess the impact of these 4DCT techniques on treatment planning for lung tumors using intensity-modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT).

Main Methods:

  • A lung phantom with spherical and tumor-shaped targets was imaged using 4DCT with 16-cm (4DCT16) and 4-cm (4DCT4) detectors.
  • Ground truth 4DCT (4DCTGT) was established via step-wise helical scans.
  • IMPT and VMAT treatment plans were created and evaluated based on dose coverage objectives on reconstructed 4DCT images and phase-sorted images.

Main Results:

  • 4DCT16 enabled IMPT plans to meet dose objectives (≥95% V_PD), achieving 98.95% for spherical and 98.27% for tumor targets.
  • 4DCT4 failed to meet dose objectives for both IMPT and VMAT plans, with significantly lower coverage.
  • 4D doses calculated using 4DCT16 closely matched those from 4DCTGT for both IMPT and VMAT plans.

Conclusions:

  • 16-cm detector 4DCT provides accurate and reliable 4D dose imaging for lung tumors, particularly with IMPT.
  • While 4DCT16 shows promise, potential uncertainties in phase sorting require consideration for optimal treatment planning.