Related Experiment Video
Updated: Apr 2, 2026
09:16
A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
Published on: January 22, 2016
16.0K
Approach With Caution: A Pilot Randomised Controlled Trial of Approach Bias Modification for People Undergoing
Victoria Manning1,2, Danielle Whelan1,2, Hugh Piercy1,2
1Monash Addiction Research Centre, Eastern Health Clinical School, Monash University, Melbourne, Australia.
Drug and Alcohol Review
|April 1, 2026
Summary
Approach bias modification (ApBM) shows potential for treating methamphetamine use disorder (MUD), but requires further research due to safety concerns. This cognitive training intervention may help improve abstinence rates in individuals with MUD.
Area of Science:
- Addiction research
- Cognitive behavioral therapy
- Clinical psychology
Background:
- Methamphetamine use disorder (MUD) has low long-term abstinence rates after residential rehabilitation.
- Approach bias modification (ApBM) is a cognitive training intervention effective for alcohol use disorder but understudied for MUD.
Purpose of the Study:
- To investigate the safety and acceptability of ApBM for MUD.
- To explore the preliminary efficacy of ApBM in reducing methamphetamine use, craving, and dependence severity.
Main Methods:
- A randomized controlled trial involving 24 MUD patients in residential treatment.
- Participants received 6 sessions of either ApBM or sham-control training.
- Outcomes including methamphetamine use, craving, and dependence were assessed at 1 and 3 months post-discharge.
Main Results:
- Some participants experienced adverse psychological reactions, leading to withdrawals in both groups.
- Completed training was generally rated as acceptable by participants in both ApBM and control groups.
- Preliminary data favored ApBM for abstinence rates at 1 and 3 months, but differences were not statistically significant due to small sample size. No significant differences were found in craving or MUD severity.
Conclusions:
- ApBM may warrant further investigation for MUD treatment.
- Caution is advised due to observed safety concerns during the intervention.
Keywords:
approach bias modificationcognitive bias modificationinpatient treatmentmethamphetamineresidential rehabilitationMore Related Videos
Related Concept Videos
01:15Drug Abuse and Addiction: Pharmacological Phenomena
1.5K
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
1.5K
01:30Attention-Deficit/Hyperactivity Disorder
1.3K
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.3K
01:24Substance Use Disorders Affecting Sleep
540
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
540
01:28Drug Therapy
408
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
408
01:21Behavior Modification
949
Behavioral approaches have often been criticized for ignoring mental processes and focusing solely on observable behavior. However, these approaches provide an optimistic perspective for individuals seeking to change their behaviors. Rather than concentrating on intrinsic personality traits, behavioral approaches suggest that even longstanding habits can be modified by changing the reward contingencies that maintain them.
A real-world application of operant conditioning principles is applied...
A real-world application of operant conditioning principles is applied...
949
01:17Drug Dependence
1.9K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.9K