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Bench Evaluation of Intraocular Pressure Control with Clinical Assessment of Anterior Chamber Stability of a Dual Peristaltic Phacoemulsification Device.

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Related Experiment Video

Updated: Apr 3, 2026

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
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Occlusion Break Surge Performance of a Next Generation Phacoemulsification System.

Kevin M Miller1, Ali Aboughaida2, David Dyk2

  • 1University of California, Los Angeles (UCLA), Los Angeles, CA, USA.

Journal of Cataract and Refractive Surgery
|April 1, 2026
PubMed
Summary

The UNITY® Vitreoretinal Cataract System (UVCS) demonstrated significantly lower occlusion break surge volumes compared to the CENTURION® Vision System with Active Sentry™ (CAS). This finding suggests UVCS may enhance surgical safety by reducing risks like posterior capsule rupture.

Keywords:
Occlusion break surgeintraocular pressurephacoemulsification

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Area of Science:

  • Ophthalmology
  • Medical Devices
  • Surgical Technology

Background:

  • Cataract surgery requires precise control of intraocular pressure (IOP) to ensure patient safety.
  • Sudden fluidic shifts, known as occlusion break surge volumes, can occur during cataract surgery, potentially leading to complications.
  • Comparing the fluid dynamics of different phacoemulsification systems is crucial for advancing surgical techniques.

Purpose of the Study:

  • To quantitatively compare the occlusion break surge volumes between the UNITY® Vitreoretinal Cataract System (UVCS) and the CENTURION® Vision System with Active Sentry™ (CAS).
  • To evaluate the impact of varying intraocular pressures, vacuum limits, and aspiration flow rates on surge volumes for both systems.

Main Methods:

  • An experimental study utilizing an eye model with average human eye compliance.
  • Testing was conducted across a range of intraocular pressures (IOPs) from 20 to 80 mmHg, vacuum limits from 300 to 650 mmHg, and aspiration flow rates of 20 and 40 cc/min.
  • A second-order polynomial model was employed to analyze and compare data, particularly at a target IOP of 20 mmHg.

Main Results:

  • The UNITY® Vitreoretinal Cataract System (UVCS) exhibited mean occlusion break surge volumes that were 44% lower than those of the CENTURION® Vision System with Active Sentry™ (CAS) across common settings.
  • At a flow rate of 40 cc/min and an IOP setpoint of 20 mmHg, UVCS demonstrated an average surge volume decrease of 46% across all tested vacuum limits.
  • The largest mean surge volume for UVCS was 48 µL, compared to 75 µL for CAS, representing 19% and 30% of average human phakic anterior chamber volume, respectively.

Conclusions:

  • The UNITY® Vitreoretinal Cataract System (UVCS) consistently produced lower mean occlusion break surge volumes compared to the CENTURION® Vision System with Active Sentry™ (CAS).
  • These findings suggest that UVCS may offer surgeons enhanced confidence when operating at lower IOPs.
  • The reduced surge volumes associated with UVCS may potentially lower the risk of posterior capsule rupture, particularly in challenging cataract surgeries.