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From Offline to Inline Without Pain: A Practical Framework for Translating Offline MR Reconstructions to Inline
Zihan Ning1, Yannick Brackenier1, Sarah McElroy1,2
1Imaging Physics and Engineering Research Department, School of Biomedical Engineering and Imaging Sciences, Kings College London, London, UK.
Magnetic Resonance in Medicine
|April 2, 2026
Summary
This study introduces an open-source framework for seamless inline deployment of magnetic resonance (MR) reconstructions, overcoming common challenges and ensuring workflow integration. The framework enables robust, scalable, and reproducible MR imaging analysis.
Area of Science:
- Medical Imaging
- Magnetic Resonance Imaging (MRI)
- Computational Imaging
Background:
- Offline magnetic resonance (MR) reconstruction methods face challenges during inline deployment.
- Common issues include scan disruption, limited multi-scan support, data format adaptation, and post-processing integration.
Purpose of the Study:
- To develop and validate a practical, open-source framework for inline deployment of established offline MR reconstruction techniques.
- To address scan disruption, multi-scan input limitations, data format variability, and scanner post-processing integration.
Main Methods:
- The framework utilizes the Gadgetron platform on Siemens scanners.
- Key features include an ISMRMRD to Siemens raw format converter, asynchronous trigger-and-retrieve, resource-aware scheduling, and integrated file management.
- Validation was performed on two Siemens scanners across SENSE, AlignedSENSE, and NUFFT reconstructions.
Main Results:
- The framework demonstrated minimal code modification for inline deployment, successfully executing reconstructions without disrupting scanner workflows.
- Automated and manual image retrieval was achieved, with scanner-based post-processing applied to custom outputs.
- Multi-sequence reconstructions were feasible for large-scale applications, with 99% of inline reconstructions retrieved successfully in 480 examinations.
Conclusions:
- The developed framework significantly reduces the technical barrier for inline deployment of offline MR reconstructions.
- It offers a robust, scalable, and post-processing-compatible solution for integrated MR imaging analysis.
- The open-source availability with documentation promotes reproducibility and community adoption.

