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Medical Digital Twin Technology for Interoperability: Challenges and Opportunities.
Tengku Ahmad Iskandar Tengku Alang1, Yeong Yeh Lee2,3, Tian Swee Tan4,5
1Centre of Biomedical Engineering, University of Cyberjaya, Sepang, Malaysia.
Biomedical Engineering and Computational Biology
|April 2, 2026
Summary
Digital twins (DT) offer transformative potential in healthcare by addressing data interoperability challenges. This review explores DT integration strategies, highlighting solutions for seamless adoption in personalized medicine.
Area of Science:
- Health Informatics
- Digital Health Technologies
Background:
- Digital twin (DT) technology is rapidly advancing across various sectors.
- Previous research has explored DT applications in healthcare, but strategies for seamless integration, especially concerning heterogeneous medical data interoperability, remain underexplored.
Purpose of the Study:
- To review the concept of digital twins (DT) and their integration into healthcare.
- To analyze challenges and opportunities related to healthcare interoperability with DT adoption.
- To provide insights for professionals to advance patient-centered and personalized medicine.
Main Methods:
- Literature review of digital twin technology in healthcare.
- Analysis of interoperability issues, including data standards, formats, and technical complexity.
- Identification of potential solutions and opportunities for DT integration.
Main Results:
- Key challenges identified include the lack of standardized protocols, non-homogeneity of data formats, and technical complexity.
- Opportunities include the development of standardized protocols, open data platforms, and enhanced semantic interoperability.
- DT integration can significantly improve healthcare data management and analysis.
Conclusions:
- Digital twins present a significant opportunity to enhance healthcare interoperability and data management.
- Addressing standardization, data formats, and technical complexity is crucial for successful DT implementation.
- DT adoption can empower personalized medicine and drive the evolution of digital health.
Keywords:
digital healthhealth informaticshealthcare 5.0healthcare interoperabilitymedical digital twinMore Related Videos
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