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Feasibility and Safety of Home Blood Transfusion for Children With Advanced Stage Cancer: Experiences From a Single

Masanaka Sugiyama1,2, Naoko Mori1,2,3, Kyogo Suzuki1,2

  • 1Akabane Zaitaku Clinic, Tokiwa Group, Tokyo, Japan.

Pediatric Blood & Cancer
|April 2, 2026
PubMed

Insights

Home-based palliative care for children with cancer is growing in Japan. Blood and platelet transfusions can be safely administered at home, improving quality of life for these young patients.

Area of Science:

  • Pediatric Oncology
  • Palliative Care
  • Hematology

Background:

  • Palliative home care for pediatric cancer patients is increasingly utilized in Japan.
  • The Tokiwa Group has experience in providing home-based palliative care.

Purpose of the Study:

  • To evaluate the safety and feasibility of home-based blood and platelet transfusions for pediatric cancer patients.
  • To assess adverse event rates in home-based transfusions compared to hospital settings.

Main Methods:

  • Retrospective analysis of data from the Tokiwa Group.
  • Review of 39 pediatric cancer patients receiving home-based palliative care between April 2018 and July 2024.
  • Analysis of 281 red blood cell and platelet transfusions administered to 16 patients at home.

Main Results:

  • Home-based transfusions were performed safely in pediatric cancer patients.
  • Adverse event rates for home-based transfusions were low (2.1%), comparable to hospital settings.
  • 16 out of 39 patients received transfusions, indicating a significant need.

Conclusions:

  • Home-based blood and platelet transfusions are a safe and viable option for pediatric cancer patients receiving palliative care.
  • Implementing home-based transfusions can potentially improve the quality of life for children with advanced cancer.
  • Further integration of home-based transfusion services may enhance pediatric palliative care models.

Keywords:
blood transfusionhome carepalliative carepediatric cancer

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